Stuart Little is a 1945 children's novel by E.B. White.
Stuart Little may also refer to:
Stuart Little (franchise), the animated media franchise based on the book Stuart Little (film), the first film Stuart Little 2, the sequel film Stuart Little 3: Call of the Wild, the second animated sequel film Stuart Little (TV series), the animated television series Stuart Little: The Journey Home, the video game based on the 1999 film Stuart Little (golfer), English golfer