Huyghe or Huyghé may refer to:
Huyghe Brewery, a Belgian brewery founded in 1906
People Armand Huyghé (1871–1944), Belgian career soldier Carlo Huyghé (1923–2016), Belgian soldier and politician Gérard-Maurice Eugène Huyghe (1909–2001), French Catholic Bishop Pierre Huyghe (born 1962), French contemporary artist René Huyghe (1906–1997), French writer Sébastien Huyghe (born 1969), French politician