Pseudopyrausta santatalis is a moth in the family Crambidae. It was described by William Barnes and James Halliday McDunnough in 1914. It is found in the United States, where it has been recorded from southern Texas and Florida. It is also found in the West Indies and Mexico.

The wingspan is about 15 mm. The forewings are white, suffused with ocherous. The hindwings are white, shaded with ocherous.Barnes & McDunnough 1914. Some new North American Pyraustinae. Contributions to the Natural History of the Lepidoptera of North America. 2(6): 226 Adults have been recorded on wing from February to October.

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