Brian Cole may refer to:
Brian Cole (musician) (1942–1972), American musician with The Association B. J. Cole (Brian John Cole, born 1946), English pedal steel guitarist Brian Cole (footballer) (born 1956), Australian footballer Brian J. Cole (born 1962), American orthopedic surgeon and professor Brian Lee Cole (born 1967), American bishop Brian Cole (politician) (born 1971), American politician, member of the New Hampshire House of Representatives Brian Cole (baseball) (1978–2001), American baseball outfielder Brian Cole II (born 1997), American football safety
See also Brian Coles (born 1964), French rugby league player