Holborow is a surname. Notable people with the surname include:
Barbara Holborow (1930–2012), Australian magistrate Eric John Holborow (1918–2009), English physician and medical researcher Jonathan Holborow (born 1943), British newspaper editor Justin Holborow (born 1996), Australian actor Marnie Holborow, Irish writer and academic Lady Mary Holborow (1936–2017) Rachel Holborow, founding member of Red Monkey Richard Holborow (born 1984), Cardiac Physiologist and Regulator Wally Holborow (1913–1986), American baseball player William Holborow (1841–1917), Australian politician