Pătrașcu is a Romanian surname. Notable people with the surname include:
Bogdan Pătrașcu (born 1979), Romanian footballer Cerasela Pătraşcu (born 1992), Romanian artistic gymnast Florin Pătrașcu (born 1986), Romanian footballer Mihai Pătrașcu (disambiguation), multiple people Nicolae Pătrașcu (1580–1627), titular Prince of Wallachia Pătrașcu cel Bun (died 1557), ruler of Wallachia
See also