John Wu Shi-zhen (; 19 January 1921 – 25 August 2014) was a Chinese Roman Catholic archbishop.
Born in China, Wu Shi-zhen was ordained a priest in 1949. On 6 September 1987, he was clandestinely consecrated as bishop, and from 1990 to 2011 was an archbishop ordinary of the Roman Catholic Archdiocese of Nanchang.
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