Thomas Jerkins House is a historic home located at New Bern, Craven County, North Carolina. It was built about 1849, and is a two-story, three-bay, side-hall plan, Italianate style frame dwelling. It has a gable roof with overhanging eaves, a full-width porch, and a two-story ell.

It was listed on the National Register of Historic Places in 1972.

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