Gottfredson is a surname. Notable people with the surname include:

Denise Gottfredson, American criminologist Don Gottfredson (1926–2002), American criminologist Floyd Gottfredson (1905–1986), American cartoonist best known for his defining work on the Mickey Mouse comic strip Gary Gottfredson (born 1947), former professor of psychology at the University of Maryland, College Park Linda Gottfredson (born 1947), professor of educational psychology at the University of Delaware Michael R. Gottfredson (born 1951), the former President of the University of Oregon

See also Floyd Gottfredson Library, a series of books collecting the first 25 years of the 45-year span of work by Floyd Gottfredson on the daily Mickey Mouse comic strip