Hirson is a surname. Notable people with the surname include:
Alice Hirson (1929–2025), American actress Baruch Hirson (1921–1999), South African activist and historian David Hirson (born 1958), American dramatist Roger O. Hirson (1926–2019), American dramatist and screenwriter
See also Saša Hiršzon (born 1972), Yugoslavian/Croatian tennis player