One Blood may refer to:

Una Sangre/One Blood Lila Downs album 2004, One Blood Tour One Blood, reggae band Barry Boom One Blood (Yothu Yindi album), an album by Yothu Yindi It's Okay (One Blood), a song by American rapper The Game One Milkali (One Blood), a song by Australian duo Electric Fields OneBlood, an American not-for-profit organization