De Berardinis, de Berardinis or Di Berardinis is a surname of Italian origin.
Notable people with the name include:
Leo de Berardinis (1940–2008), Italian stage actor and theatre director Michael Di Berardinis, American public official in Pennsylvania Olivia De Berardinis (b. 1948), American painter and illustrator Ralph DeBerardinis, American physician-scientist Rosetta DeBerardinis, American artist Willie Dennis, born William DeBerardinis, American jazz trombonist