Agnew is an unincorporated community in Lancaster County, Nebraska, United States. The population was 30 at the 2020 census.

History A post office was established at Agnew in 1886, and remained in operation until it was discontinued in 1978. The community was named for William James Agnew, a railroad official. A 1925 edition is available for download at University of Nebraska—Lincoln Digital Commons. Agnew was platted in 1889.

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