Saint-Sébastien may refer to:
France Saint-Sébastien, Creuse, in the Creuse département Saint-Sébastien, Isère, in the Isère département Saint-Sébastien-d'Aigrefeuille, in the Gard département Saint-Sébastien-de-Morsent, in the Eure département Saint-Sébastien-de-Raids, in the Manche département Saint-Sébastien-sur-Loire, in the Loire-Atlantique département
Canada Saint-Sébastien, Estrie, Quebec, Le Granit, Quebec Saint-Sébastien, Montérégie, Quebec, Le Haut-Richelieu, Quebec
See also Saint Sebastian (disambiguation) San Sebastian (disambiguation) Sankt Sebastian, a former municipality in the district of Bruck-Mürzzuschlag in the Austrian province of Styria