Issy is a given name. Notable persons with that name include:
Issy Bonn (1903-1977), British actor Issy van Randwyck, English actor Issy Sharp (born 1931), Canadian hotelier and writer Issy Smith (1890-1940), British-Australian soldier Issy Wong (born 2002), English cricketer Issy Wunder (born 2003), Canadian ice hockey player
See also GPSO 92 Issy, French women's football team