The 1950–51 Copa México was the 35th staging of the Copa México, the 8th staging in the professional era.

The competition started on May 6, 1951, and concluded on May 27, 1951, with the final, in which Atlante lifted the trophy for the second time ever with a 1–0 victory over Guadalajara.

This edition was played only by 12 teams, in a knock-out stage, in a single match.

First round

Played between May 6 and May 8

Bye: Marte and Necaxa

Quarterfinals

Played May 13

Bye: Atlante

Play-off

Played May 15

Semifinals

Played May 20

Play-off

Played May 22

Final

Played May 27

Copa México 1950-51 WinnersAtlante2nd Title

References Mexico - Statistics of Copa México in season 1950/1951. (RSSSF)