Schlesser is a surname. Notable people with the surname include:
Félicie Erpelding-Schlesser (1883–1970), Luxembourgish municipal politician
Émile V. Schlesser (born 1986), Luxembourgish film director, screenwriter, composer, and multimedia artist Jean-Louis Schlesser (born 1947), French racing driver Jo Schlesser (1928–1968), French racing driver