Copello is a Spanish-language surname that may refer to:
Alexis Copello (born 1985), Cuban triple jumper Alfredo Copello (1903–?), Argentine boxer Anna Carina Copello (born 1981), Peruvian dancer and musician Eduardo Copello (1926–2000), Argentine racing driver Santiago Copello (1880–1967), Argentine Cardinal of the Roman Catholic Church Yasmani Copello (born 1987), Cuban-Turkish hurdler Maria Pia Copello, fictional character in Peruvian television series Maria Pia & Timoteo
See also Capello, a similar Italian surname