S. maculata may refer to:
Sabatia maculata, a plant endemic to the eastern United States Saccogaster maculata, a viviparous brotula Salisia maculata, a herbaceous plant Sarangesa maculata, an African butterfly Scapteira maculata, a lizard endemic to northwestern Africa Scardamia maculata, a geometer moth Schinia maculata, a flower moth Scolia maculata, a very large wasp Selenaria maculata, a moss animal Setia maculata, a sea snail Shebania maculata, a snout moth Sigapatella maculata, a sea snail Sillago maculata, a coastal marine fish Siphona maculata, a tachina fly Skenea maculata, a sea snail Solariella maculata, a top snail Spermophora maculata, a cellar spider Spiloconis maculata, a net-winged insect Squilla maculata, a mantis shrimp Stachyris maculata, an Old World babbler Stagmomantis maculata, a mantis native to the Americas Stathmopoda maculata, a concealer moth Statilia maculata, a praying mantis Stauntonia maculata, a flowering plant Stellognatha maculata, a flat-faced longhorn Stomatella maculata, a sea snail Stratiomys maculata, a soldier fly Subula maculata, an auger snail Swanka maculata, a mud turtle Symbolia maculata, a long-legged fly Synapta maculata, a sea cucumber Synaptula maculata, a sea cucumber Synemon maculata, a diurnal moth