M. maculata may refer to:
Mabuya maculata (Demerara), a Guyanese skink Mabuya maculata (Fernando de Noronha), a Brazilian skink Macrocallista maculata, a bivalve mollusc Macrothele maculata, a mygalomorph spider Maculatoscelis maculata, a praying mantis Madecassina maculata, a ground beetle Mancopsetta maculata, a southern flounder Medicago maculata, a plant native to the Mediterranean Basin Megascolia maculata, a former name for Regiscolia maculata, a scoliid wasp Megilla maculata, a ladybird beetle Mahehia maculata, a woodlouse endemic to Seychelles Margarita maculata, a sea snail Melanoraphia maculata, a ringed worm Mene maculata, a disk-shaped fish Mesovipera maculata, a venomous viper Mitromorpha maculata, a sea snail Mormodes maculata, an orchid endemic to Mexico Musca maculata, a European fly Mycena maculata, a saprotrophic fungus Myopopone maculata, a social insect