Charlotte River may refer to:
Charlotte River (Florida), former name for a presumed waterway in Florida, United States Charlotte River (Grenada), in Saint John Parish, Grenada Charlotte River (Michigan), tributary of the St. Marys River in Chippewa County, Michigan, United States Charlotte Creek (New York) (previously Charlotte River), a tributary of the Susquehanna, New York, United States
See also Shallotte River, in Brunswick County, North Carolina, United States