Nyssicus quadriguttatus is a species of beetle in the family Cerambycidae. It was described by Swederus in 1787.Bezark, Larry G. A Photographic Catalog of the Cerambycidae of the World . Retrieved on 22 May 2012.
This species is endemic to Central America and northern South America, specifically Bolivia, Brazil, Ecuador, Guyana, Honduras, and Venezuela.
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