Avilés is a Spanish surname. Notable people with the surname include:
Alicia Avilés, educator and community leader in Costa Rica Caleb Avilés, former member of the boy band MDO Daniel Avilés (born 2001), Spanish actor Gabriel de Avilés, 2nd Marquis of Avilés (–1810), governor of Chile, viceroy of Río de la Plata, and viceroy of Peru Joseph B. Aviles Sr. (1896–1990), Puerto Rican born officer in the United States Navy and Coast Guard Lila Avilés (born 1982), Mexican film director, screenwriter, actress and producer
Lucho Avilés (1938–2019), Uruguayan-born Argentine journalist and television presenter Luis Avilés (born 1990), Argentine professional footballer Óscar Avilés (1924–2014), Peruvian musician Pedro Avilés (born 1956), Spanish writer Pedro Menéndez de Avilés (1519–1574), first governor of Spanish Florida and governor of colonial Cuba Ramón Avilés (1952–2020), Puerto Rican baseball player Raúl Avilés (born 1964), Ecuadorian footballer René Avilés Fabila (1940–2016), Mexican writer Tomás Avilés (born 2004), Argentine professional footballer