Christopher Willoughby may refer to:
Christopher Willoughby (MP) (by 1508–70), MP for Wilton and Wiltshire Christopher Willoughby-Drupe, Tintin character Christopher Willoughby, 10th Baron Willoughby de Eresby (1453 – 1498/1499) Sir Christopher Willoughby, 1st Baronet (1748–1808) of the Willoughby baronets Sir Christopher William Willoughby, 2nd Baronet (1793–1813) of the Willoughby baronets Christopher Willoughby, executive of the World Bank Group Chris Willoughby, pseudonym of Amy Witting