Handle with Care may refer to:

Film and television Handle with Care (1922 film), an American silent film by Phil Rosen Handle with Care (1932 film), an American pre-Code film by David Butler Handle with Care (1935 film), a British comedy by Randall Faye Handle with Care (1958 film), an American film by David Friedkin Handle with Care (1977 film), an American comedy by Jonathan Demme Handle with Care (1985 film), an Australian telefilm by Paul Cox Handle With Care (TV series), an American television series about the United States Postal Service "Handle with Care" (The Vampire Diaries), a 2013 episode of The Vampire Diaries Handle with Care (2017 film), a Norwegian film by Arild Andresen Handle with Care (Fear the Walking Dead), an episode of the television series Fear the Walking Dead "Handle with Care", an episode of the Netlifx cartoon series The Cuphead Show!

Music Albums Handle with Care (Clarke-Boland Big Band album) (1963) Handle with Care (Natalie Lauren album) Handle with Care (Nuclear Assault album) (1989) Handle with Care, a 2001 album by Johnny Jenkins

Songs "Handle with Care" (song), a 1988 song by the Traveling Wilburys "Handle with Care", a 1966 song by Teresa Brewer "Handle with Care", a 2015 song by Kid Cudi from Speedin' Bullet 2 Heaven

Other uses Handle with Care (novel), a 2009 novel by Jodi Picoult