Challis may refer to:
People Challis (surname)
Places Challis, Idaho Challis, New Zealand
Other uses Challis (crater), a crater on Earth's moon Challis railway station "Challis", a song by American heavy metal band Dio off their 2000 studio album Magica Challis (fabric), a printed woven fabric.
See also Chalice, a cup used in ceremonies such as the Eucharist Chalise, a surname