Bark isolates are chemicals which have been extracted from bark. Prominent medical examples are salicylic acid (active metabolite of aspirin) and paclitaxel (Taxol). The pharmacology of bark isolates is an ongoing topic of medical research.
Isolate Bark source Researched activity Paclitaxel, taxanes Taxus chemotherapeutic Paeonol Paeonia suffruticosa various Honokiol, 4-O-methylhonokiol, magnolol, obovatol Magnolia neurotrophic & anti-inflammatory Salicylic acid Salix alba antipyretic, analgesic Yohimbine, corynanthine, ajmalicine, rauwolscine west African evergreen MAOI, stimulant beta-carbolines, harmala alkaloids numerous MAOI Cinnamon, camphor, cinnamaldehyde Cinnamomum blood sugar stabilizer, antioxidant Quinine, quinidine, cinchonidine, cinchonine Cinchona antipyretic, analgesic, antimalarial Safrole Sassafras Huáng bǎi Amur cork tree (Phellodendron amurense) TCM Strictamine Alstonia scholaris Slippery Elm (Ulmus rubra) demulcent Geniposidic acid Eucommia ulmoides N-methyltryptamine, serotonin analogs numerous species from Brazil, Mexico, Taiwan serotonin agonist, neuroimmunologic modulator Quassin Quassia amara various Celastrol Tripterygium wilfordii various Mitraphylline Cat's claw (Uncaria tomentosa) anti-inflammatory Ellagic acid, rutin, gallic acid, ethyl gallate Ailanthus altissima various Coronaridine, voacangine, ibogamine, ibogaine, tabernanthine Voacanga africana, Tabernanthe iboga neuroimmunologic modulator Lapachol, quercetin Pau D'Arco (Handroanthus impetiginosus) therapeutic naphthoquinone Icariin Eucommia PDE5 inhibitor Baicalin Oroxylum indicum prolyl endopeptidase inhibitor Frankincense, incensole Boswellia sacra, Boswellia incensole is a TRPV3 agonist QS21 Quillaja saponaria (soap bark tree) potential immunologic adjuvant Sandalwood oil, α-Santalol, β-Santalol Sandalwood (Santalum) Ayurvedic component Bergenin, α-viniferin, ε-viniferin, diptoindonesin A Bergenia ligulata, Dryobalanops aromatica, Mallotus japonicus component of Ayurvedic medicine "Paashaanbhed" Phenolic lactones Caesalpinia paraguariensis component of Bolivian traditional medicine Erythravine Erythrina mulungu Brazilian medicinal plant Antimicrobial, anti-inflammatory compounds Psidium guajava (Guava tree) component of traditional medicine Perfume resin Agarwood / Oud Wood aromatherapy Opopanax, balsam, bdellium, bisabol Myrrh (Commiphora) component of Eastern-Mediterranean, Middle-Eastern, and North-African, traditional medicine Rotenoids, piscidone Jamaican dogwood (Piscidia piscipula) component of Caribbean traditional medicine
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