Vasco Fernandes may refer to:
Vasco Fernandes (artist) (c. 1475-c. 1542), Portuguese Renaissance painter Vasco Fernandes Coutinho, captain of Espírito Santo (1490–1561), the founder of the Brazilian state of Espírito Santo Vasco da Gama Fernandes (1908–1991), Portuguese lawyer and politician Vasco Fernandes (footballer) (born 1986), Portuguese footballer