Esiri is a name predominantly used by the Urhobo people of the Niger-Delta region of Nigeria. It can either be a forename or surname. You also have it in compound names e.g. Esiri-Okotete. Notable people with the surname include:

Arie Esiri, Nigerian photographer and filmmaker, twin brother of Chuko Esiri Allie Byrne Esiri (born 1967), English actress and writer Chuko Esiri, Nigerian filmmaker and screenwriter, twin brother of Arie Esiri Justus Esiri (1942–2013), Nigerian actor Sidney Onoriode Esiri (born 1980), better known as Dr SID (Dr Sid), Nigerian singer-songwriter