Esch is a surname. Notable people with the surname include:

Arno Esch (1928–1951), German politician Edward Esch (born 1970), lyricist for, and possibly pseudonym of, composer Eric Whitacre En Esch (born 1968), German musician Eric Esch (born 1966), American boxer better known as Butterbean Jake Esch (born 1990), American baseball player Jan van Essen (died 1523), one of the first two Lutheran martyrs, whose surname was often rendered Esch in German writings. John J. Esch (1861–1941), American attorney and politician Marvin L. Esch (1927–2010), U.S. Representative from Michigan Mathilde Esch (1815–1904), Austrian genre painter Natasha Esch, Canadian model Nicolaus van Esch (1507–1578), Dutch theologian Vincent Esch (1876–1950), British architect

See also Von der Esch, surname Oesch, surname Eash, surname