Mano a Mano may refer to:
Mano-A-Mano, a professional boxing event between Manny Pacquiao and Óscar Larios Mano a Mano, an album by Grupo Bryndis Mano a Mano, a collaboration album by Luis Eduardo Aute and Silvio Rodríguez "Mano a Mano", a 2018 song by Salvador Sobral "Mano A Mano", a song by Hall & Oates from the 1981 album Private Eyes "A mano a mano", a 1978 song by Riccardo Cocciante
See also Mano Mano (disambiguation)