William McLaughlin may refer to:
Bill McLaughlin Australian rugby union player Billy McLaughlin, American political strategist Billy McLaughlin, American musician Willie McLaughlin (1878–1946), Scottish footballer William McLaughlin (baseball) (1861–1936), Major League Baseball shortstop William McLaughlin (politician) (born 1932), American politician from Michigan William I. McLaughlin (born 1935), retired American space scientist