William Lowe may refer to:
Sports William Lowe (cricketer) (1873–1945), English cricketer William Lowe (footballer) (1877–1957), English footballer William O. Lowe (1894–1949), American college football player William Lowe (athlete) (1901–?), Irish sprinter William Lowe (bowls), Scottish lawn bowls player Arch Lowe (William Archibald Burnside Lowe, 1875–1942), Australian rules footballer Kid Lowe (William McKinley Lowe, 1900–1988), American baseball player
Others William Lowe (British Army officer) (1861–1944) William Lowe (civil servant) (1831–1862), British district magistrate and civil servant in India William C. Lowe (1941–2013), IBM executive and "Father of the IBM PC" William Drury Lowe (landowner, born 1753), British merchant of Bread Street made High Sheriff of Derbyshire in 1795 William Drury Lowe (landowner, born 1802) (1802–1877), English landowner and High Sheriff of Derbyshire William Henry Lowe (died 1900), Scottish physician and amateur botanist William James Lowe, Canadian politician William M. Lowe (1842–1882), American politician in Alabama William Warren Lowe (1831–1898), Union Army officer