Macel is an unincorporated community located in Tallahatchie County, Mississippi. Macel is approximately south of Tippo and approximately north-northeast of Philipp on Tippo Road.

Macel is named from Macel Willingham, the daughter of a local landowner.

A post office operated under the name Macel from 1908 to 1955.

Macel is located on the former Illinois Central Gulf Railroad and in 1920 had a population of 100.

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