Wilkes may refer to:
Places Wilkes, Portland, Oregon, a US neighborhood Wilkes County, Georgia Wilkes County, North Carolina Wilkes Basin, George V Land, Antarctica Wilkes Station, Antarctica, a research station Battery Wilkes, a historic artillery battery in West Ashley, Charleston, South Carolina Wilkes Power Plant, Jefferson, Texas, an electrical power station Wilkes Island, islet of Wake Island in the Central Pacific.
Schools in the United States Wilkes University, Pennsylvania Wilkes Community College, Wilkesboro, North Carolina Wilkes Honors College, Florida
People John Wilkes, English radical journalist and politician in the late 18th century. Wilkes (surname), other people with the surname Wilkes Angel (1817–1889), New York lawyer and politician Wilkes C. Robinson (1925–2015), judge of the United States Court of Federal Claims from 1987 to 1997
Other uses , several US Navy vessels Wilkes (horse) (born 1952), Australian thoroughbred
See also Wilk Wilken Wilkens Wilkes Land, Antarctica Clarie Coast, called Wilkes Coast in Australia Wilkes-Barre, Pennsylvania, a city Wilkes-Barre Township, Luzerne County, Pennsylvania Wilkes-Barre Variation, a chess opening Wilks (disambiguation)