Heusser is a surname. Notable people with the surname include:
Andreas Heusser (born 1976), Swiss artist and curator Ed Heusser (1909–1956), American basketball player Felipe Heusser (born 1980), Chilean activist Jakob Heusser (1862–1941), Swiss industrialist Johanna Spyri (née Heusser) (1827-1901), Swiss novelist Roger Heusser (born 1941), American Civil Servant Matthew Heusser (born 1976), American Technology Consultant, Author and Entrepreneur/Investor Meta Heusser-Schweizer (1797–1876), Swiss poet