This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence.Truven Health Analytics, Inc. DrugPoint® System (Internet) [cited 2013 Oct 1]. Greenwood Village, CO: Thomsen Healthcare; 2013.OLEPTRO (trazodone hydrochloride) tablet, extended release OLEPTRO (trazodone hydrochloride) tablet, extended release [Angelini Pharma Inc.] [Internet]. DailyMed. 2013 [cited 2013 Oct 1]. Available from: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=88c45123-f475-4dd0-bbac-c261868924eftrazodone (Rx) -Desyrel, Desyrel Dividose [Internet]. Medscape Reference. [cited 2013 Oct 1]. Available from:http://reference.medscape.com/drug/oleptro-trazodone-d-342965
Very common Very common (>10% incidence) adverse effects include: Blurred vision Dizziness Somnolence Dry mouth Nausea Headache Fatigue
Common Common (1–10% incidence) adverse effects include: Vomiting Constipation Diarrhea Backache Confusion Insomnia Dream disorder (abnormal dreaming) Disorientation Incoordination Nasal congestion Orthostatic hypotension Syncope Tremor Weight change Anxiety Hypotension Oedema Dysgeusia Memory impairment Migraine Paraesthesia (feelings of "pins and needles") Agitation Dyspnoea Night sweats
Uncommon Uncommon (0.1–1% incidence) adverse effects include: Hypersensitivity reaction Muscle twitching Amnesia Aphasia Hypoesthesia Speech disorder Bladder pain Urinary incontinence Gait disturbance Reflux oesophagitis Dry eye Eye pain Photophobia Hypoacusis Tinnitus Vertigo Acne Hyperhidrosis Photosensitivity reaction Flushing
Rare Rare (<0.1%) adverse effects include: Urinary retention Prolonged QT interval Torsades de Pointes Ataxia Breast enlargement or engorgement Lactation Cardiospasm Stroke Chills Cholestasis Clitorism Congestive heart failure Diplopia Extrapyramidal symptoms Hallucinations Haemolytic anaemia Hirsutism Hyperbilirubinaemia Increased amylase Increased salivation Leukocytosis Leukonychia Jaundice Liver enzyme alterations Methemoglobinemia Paraesthesia Paranoia Stupor Rash Seizure Priapism Pruritus Psoriasis Psychosis Suicidal ideation Suicidal behaviour Syndrome of inappropriate antidiuretic hormone secretion Tardive dyskinesia Serotonin syndrome Unexplained death Urticaria Vasodilation
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