This is a list of notable people with Down syndrome, a condition also known as Down's syndrome or trisomy 21. Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is typically associated with developmental delays, characteristic physical features, and mild to moderate intellectual disability. The average IQ of a young adult with Down syndrome is 50, equivalent to the mental age of an 8- or 9-year-old child, but this number varies widely. At the same time, they enjoy a rich social and emotional awareness.L. Hippolyte, K. Iglesias, M. Van der Linden & K. Barisnikov (August 2010). "Social reasoning skills in adults with Down syndrome: the role of language, executive functions and socio-emotional behaviour". Journal of Intellectual Disability Research (doi: 10.1111/j.1365-2788.2010.01299.x): 1. Down syndrome is the most common chromosome abnormality in humans, occurring in about one per 1000 babies born each year.
A–Z
NameDetailsLifespanCountrySourceGerman royalty1915–1980Spain's first city councillor with Down syndromeb. 1983Actor who starred in The Ringerb. 1977Actor and reality star who appeared on The Suspicions of Mr Whicher and The Undateablesb. 1985Celtic F.C. fanb. 2003Actress who appeared in American Horror Story: Murder House and American Horror Story: Covenb. 1985Actor and folk singer, best known for his role in Life Goes On as character Charles "Corky" Thacherb. 1965Queen consort of the Kingdom of France; diagnosis is speculative.1499–1524Trisomie et handicaps génétiques associés, Elsevier-Masson, Abrégés, 5e éd, 2007, Monique Cuilleret, p. 5 https://archive.org/details/trisomie-et-handicaps-genetiques-associesFirst college football player with Down syndrome to play and score in an official gameb. 1999Disability rights advocateb. 1995Multi-instrumentalist who has performed in over 13 countries and almost all states, first person with Down syndrome to play in Carnegie Hall.b. circa 1983Entrepreneur who started Collettey's Cookiesb. 1990Actor who won the Best Actor Award at the 1996 Cannes Film Festival for his role in The Eighth Dayb. 1970Actress who appeared in Life Goes On and the Family Guy episode "Extra Large Medium"1970–2023DSIAM—Down Syndrome in Arts & Media website. Retrieved 02-18-10.Disability rights campaigner and the first living person with Down syndrome to receive an honorary doctorate degreeb. 1977Member of the Corts Valencianesb. 1978 or 1979Youngest child of Charles and Yvonne de Gaulle1928–1948Actor who was nominated for a Genie Award for his role in Café de FloreUnknownNewspaper salesman, poet and painter1938-2020Actress, playwright, writer and disability rights activistb. 1982Joswig, Rebekka (9 June 2012). "Marte Wexelsen Goksøyr får Stolthetsprisen ". Vårt Land. Retrieved 7 March 2014.Model who has appeared on the cover of British Vogueb. 2001Actress who has appeared in Upstairs Downstairs and Call the Midwifeb. 1976Actor with the leading role in Peanut Butter Falcon and first presenter in the history of the Academy Awards with Down syndromeb. 1985The first person with Down syndrome to receive a heart–lung transplantd. 1997Actor, author and activist who starred in Line of Duty and Coming Down the Mountain and played Hamlet with Blue Apple Theatreb. 1985Actor who appeared in 55 episodes of Sesame Streetb. 1974Actor who starred in Pradhama Drishtiya Kuttakkarb. 1987 Disability rights activist, France's first municipal councillor and recipient of the Ordre national du Mériteb. 1985Water boy, supporter and mascot of Vaqueros de Bayamón and Puerto Rico men's national basketball teamb. 1970Rapperb. 1982Edmonton Oilers locker room attendant1963–2020First person with Down syndrome to complete an Ironman triathlonb. 1999Actor who starred in the film Yo También. First student with Down syndrome in Europe to obtain a degree.b. 1974Actress who played Becky Jackson in Gleeb. 1990Actress who starred in Champions, first intellectually disabled Goya Awards nomineeb. 1993English actor and journalist, best known for his role as Finn McLaine in The Dumping Groundb. 2000BAFTA Scotland award–winning actress who appeared in AfterLifeb. c. 1980Actress, appeared in 2023 The Hunger Games: The Ballad of Songbirds & Snakesb. c. 2009Football fan and socialite. Official mascot of the Brave Warriors, Namibia's national football team1967–2017Artist, writer, and social activistb. 1976Outsider sculptor and fiber artist1943–2005Actress known for her role in Salatut elämätb. 1977First fashion designer with Down syndrome to be featured in London Fashion Weekb. 1997Disability advocate who testified before US Congress in 2017 to explain that he regarded the abortion of fetuses with Down syndrome as immoral.b. 1982Model, Brand Representative First professional model with Down syndrome to represent an international skincare line.b. 1996Model who walked at New York Fashion Week, hailed as the first professional model with Down syndromeb. 1996Actress, talk show hostUnknownJenna Benchetrit, "'I'm proving everyone wrong': Actors with Down syndrome enjoying new era of media representation". CBC News, February 19, 2022.An infant who was born after an unsuccessful abortion attempt and subsequently fostered1997–2019World and European champion track and field athleteb. 1998Man who was shot 25 times by Swedish policeb. 1997American sociologist and heart transplant recipient, known for disability rights activismb. 1989 or 1990Actor who starred in The Secret Life of the American Teenagerb. 1979
Fictional C.J. Casagrande, 13-year-old boy in cartoon series The Casagrandes.
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