Höfle is a Germanic surname. Notable people with the surname include:
Frank Höfle (born 1967), German Paralympic athlete Hermann Höfle (1911–1962), Austrian Nazi SS officer and Holocaust perpetrator Hermann Höfle (SS general) (1898–1947), German Nazi SS general Heiderose Wallbaum (born 1951), full name Adelhied Wallbaum-Höfle, West German sprint canoer
See also Höfle Telegram, a document discovered in 2000 which reveals statistical information about the Holocaust