Henry Street Historic District is a national historic district located at Roanoke, Virginia. It encompasses four contributing buildings constructed between 1917 and 1951. They were developed as the central business and entertainment district for the African-American neighborhood of Gainsboro in Northwest Roanoke. They are the Hotel Dumas (1917), The Strand Theatre (1923), Dr. Lylburn Downing office (c. 1945), and a commercial building (1951). and Accompanying four photos and Accompanying map

It was listed on the National Register of Historic Places in 2004. The buildings are also included in the Gainsboro Historic District.

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