Hypercompe simplex is a moth of the family Erebidae first described by Francis Walker in 1855. It is found in Puerto Rico, as well as on the Virgin Islands and the Lesser Antilles. Note: This source places Hypercompe simplex as a synonym of Hypercompe icasia.
The larvae feed on Cedrella, Cissus, Erechtotes, Erythrina, Ipomaea and Solanum torvum.
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