Frank Frost (1936–1999) was an American blues musician.

Frank Frost may also refer to:

Frank Frost (soccer), American football player at the 1904 Summer Olympics Frank A. Frost (1874–1947), New York state senator Frank Dutton Frost (1882–1968), British Army officer Frank J. Frost (1929–2026), American scholar of Ancient Greek history, archaeologist, politician, and novelist Frank Frost, a member of the Big Five (Scotland Yard)

See also Francis Theodore Frost (1843–1916), Canadian politician Francis Seth Frost (1825–1902), painter, photographer and businessman