Metazosin is an antihypertensive α1-adrenergic receptor antagonist. Synthesis The amide (3) is formed when piperazine is reacted with 2-methoxypropionylchloride…
Metazosin is an antihypertensive α1-adrenergic receptor antagonist. Synthesis
The amide (3) is formed when piperazine is reacted with 2-methoxypropionylchloride (2). Metazosin is the product when this intermediate is reacted with the substituted quinazoline (4).
References
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