John Henry Smith (1848–1911) was a member of the Quorum of the Twelve Apostles and the First Presidency of The Church of Jesus Christ of Latter-day Saints.

John Henry Smith may also refer to:

J. H. Smith (mayor) (1858–1956), mayor of Everett, Washington and co-founder of Anchorage, Alaska John Henry Smith (politician) (1881–1953), Australian politician John Henry Smith (reporter) (21st century), American sports journalist John H. Smith (bishop) (1939–2012), bishop of the Episcopal Diocese of West Virginia