Ophidion is a genus of flowering plant in the family Orchidaceae, native to Panama to western South America and Venezuela. The genus was established by Carlyle A. Luer. It has been included in a broad circumscription of Phloeophila, but there is evidence that it forms a monophyletic taxon, and it is accepted by Plants of the World Online.

Species , Plants of the World Online accepted the following species: Ophidion alphonsianum (L.E.Matthews) Karremans & J.S.Moreno Ophidion barbilabium (Vierling) Karremans & J.S.Moreno Ophidion carrilloi P.Ortiz Ophidion compactum (Vierling) Karremans & J.S.Moreno Ophidion cunabulum (Luer & R.Escobar) Luer Ophidion cymbula (Luer) Luer Ophidion dasyglossum (Luer & R.Escobar) Luer Ophidion doucetteanum (L.E.Matthews) Karremans & J.S.Moreno Ophidion erectilabrum Reina-Rodr., O.Pérez & Bogarín Ophidion juan-felipei (Vierling) Karremans & J.S.Moreno Ophidion markertii (Vierling) Karremans & J.S.Moreno Ophidion nekidapono J.S.Moreno & Karremans Ophidion nigerrimum (Vierling) Karremans & J.S.Moreno Ophidion orchidoides A.Doucette Ophidion pallidiflorum (Vierling) Karremans & J.S.Moreno Ophidion parvum (Vierling) Karremans & J.S.Moreno Ophidion pleurothallopsis (Kraenzl.) Luer

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