Thirkleby may refer to: Thirkleby High and Low with Osgodby, a civil parish in the former Hambleton District, North Yorkshire, England, which includes the villages of Great Thirkleby and Little Thirkleby Thirkleby, Kirby Grindalythe, a hamlet in the parish of Kirby Grindalythe, in the former Ryedale District, North Yorkshire, from which Roger of Thirkleby's name was derived.
See also Thirkleby Hall, a demolished 18th-century house in Great Thirkleby