Ene is both a given name and a surname.
Given name Ene Ergma (born 1944), Estonian politician Ene Järvis (1947–2025), Estonian actress Ene Kaups (born 1963), Estonian politician Ene Mihkelson (1944–2017), Estonian writer Ene Franca Idoko (born 1985), Nigerian sprinter Ene Rämmeld (born 1947), Estonian actress Haide-Ene Rebassoo (1935–2018), Estonian botanist Ene Riisna (born 1938), Estonian-American television producer Ene-Liis Semper (born 1969), Estonian video artist, performance artist, scenographer and theatre director Ene-Margit Tiit (born 1934), Estonian mathematician and statistician
Surname Alexandru Ene (1928–2011), Romanian footballer Ana Derșidan-Ene-Pascu (1944–2022), Romanian fencer Gheorghe Ene (1937–2009), Romanian footballer Gigel Ene (born 1982), Romanian footballer Noni Răzvan Ene (born 1992), Romanian singer Orhun Ene (born 1967), Turkish former professional basketball player