Helou, Hélou or Helu is a surname that means "sweet" or "pretty" in Arabic. Notable people with the surname include:
Abdul Latif Helou (born 1971), Syrian footballer Anissa Helou (born 1952), British food writer of Lebanese/Syrian descent Carlos Slim Helu (born 1940), Mexican business magnate of Lebanese descent Charles Helou (1913–2001), President of Lebanon Henri Helou, Lebanese politician and Member of Parliament John Helou (died 1823), Lebanese religious leader Nina Helou (1904–1989), Lebanese lawyer and First Lady