Spikes is the surname of:
Brandon Spikes (born 1987), American National Football League (NFL) linebacker Cameron Spikes (born 1976), American former NFL football guard Charlie Spikes (born 1951), Major League Baseball player Irving Spikes (born 1970), American former NFL running back Jack Spikes (born 1937), former American collegiate and American Football League running back and placekicker John Spikes (1881–1955), American jazz musician and entrepreneur Ken Spikes (1935-2009), former NASCAR Cup Series driver Reb Spikes (1888–1982), American jazz saxophonist and entrepreneur Richard Spikes (1884–1962), African-American engineer Takeo Spikes (born 1976), American NFL linebacker
See also Spike (surname)