Simcox is a surname. Notable people with the surname include:
A. J. Simcox, American baseball player Carroll Eugene Simcox, American Episcopal priest and editor of The Living Church magazine Chris Simcox, American co-founder of the Minuteman Civil Defense Corps (MCDC) Christopher Simcox, English double murderer Edith Simcox, British writer and feminist George Augustus Simcox, British classical scholar Grover Simcox, American illustrator Robert Simcox, American talk radio host Robin Simcox, incumbent Commissioner for Countering Extremism Tom Simcox, American former actor